Is it true that blood type and Rh factor can change throughout life?

On the Internet regularly Appear stories About how someone at first determined one blood group or Rh factor, and over life, these characteristics have changed. Typically, the authors of the stories associate this with taking certain therapy, pregnancy, but most often with bone marrow transplantation or blood transfusion. We decided to check whether a person can actually change a blood type and/or Rh factor.

Information about the blood group and Rh factor Maybe To be entered into a civil passport at the request of a person. However, the definition of these characteristics can be necessary for a person mainly in the case of planned large operations or after serious injuries, as well as when planning pregnancy. People may not know their blood group and Rhesus Factor for a long time.

In order to answer the question made in the title, you need to understand what determines these parameters. According to the most common Classification Four blood groups are distinguished, which are called by numbers, in official documents they are called 0 (I), A (II), B (III) and AB (IV). The blood group is determined by the absence or the possibility of the possibility of maintaining two antigen molecules on the surface of red blood cells. Not a single one can attach - the first, can only attach A - the second, it can contain only B - the third, has the ability to attach both - fourth. 

In addition to A and B, on the surface of red blood cells normally are located and other antigens. In particular, for the first time found in Makaki-Rezus-Rh factor to Antigen D. If the possibility of attachment, a person is considered a Rh-positive person, and in the absence of Rh-negative. Thus, the key parameter for determining the blood type and the Rh factor is not the presence of an antigen on the surface, but the possibility of its attachment. However, with some oncological, genetic and infectious diseases (bone marrow cancer, talassemia, HIV, hepatitis), as well as with chemical poisoning and even taking certain therapy in the blood thrown out An enzyme that unholes part of the molecule A and that becomes similar to the antigen B. During pregnancy, the body Maximizes The production of red blood cells, while the production of antigens remains the same. Thus, the ratio of the number of red blood cells and antigens changes. This can also lead to improper test results. That is, a blood type does not change, but a laboratory error occurs.

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In theory, the change of blood type possible In the case of bone marrow transplantation and complete replacement of the circulating blood of the donor. However, in practice, such a procedure is impossible when the blood and recipient’s characteristics are not consumed, since in this case the recipient lymphocytes will immediately begin the attack on the transplanted bone marrow, which will lead To the reaction "transplant against the owner", and in the future - to the death of the recipient.

Thus, all the blood group and the Rh factor described by users of the “change” are actually erroneous test results. In reality, these characteristics in humans change Can't.

Фейк

Fake

What do our verdicts mean?

Read on the topic:

  1. Myths about blood donation - Blood Center of the FMBA of Russia 
  2. Maria Idrisova - on the eve of bone marrow transplantation

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