Is it true that the inventor of the PCR stated that the test should not be used to diagnose any diseases?

The information is distributed that Carey Mullis, the creator of the PCR method, said that his test should be used only for scientific purposes, and it is not suitable for diagnosis, since the test can give false positive results and show the presence of viruses, which a person does not have. We decided to check if the scientist actually adhered to this opinion.

About this position of an American researcher writes "Red Spring", and also numerous Pseudo -Demedic sites And Forums. Users distribute the same information Facebook, "VKontakte", Telegram And Instagram. In the context of criticism of PCR testing for coronavirus infection to him attributed The phrase: “To do this throughout the population is a scientific heresy. Many of my colleagues - clinicians, scientists who approve of such tests - should be ashamed! This is most shocking me. ”

PCR is a polymerase chain reaction that can detect any pathogen in the sample if at least its slightest particle is present. The PCR diagnostics method helped doctors to the pandemic of coronavirus infection-its They think One of the most sensitive and accurate tests. The PCR method is detected by many infections transmitted sexually (chlamydia, gonorrhea, herpes, guard, HPV, HIV), carry out differential diagnosis of bacterial and viral pneumonia (including coronaviral pneumonia), determine the presence of respiratory infections, identify a Helicobacter, and they use it for diagnosis Salmonellosis, diphtheria, viral hepatitis and cytomegalovirus infection.

Carey Mullis. Source

Her discoverer Kary Mullis was born in 1944 in North Carolin. Boy since childhood Different With a craving for experiments - according to him, at the age of 14 he used a mixture of sugar with potassium nitrate to create fuel for a home -made rocket. She successfully took off a whole kilometer, and her passenger - the frog smeared with asbestos calmly returned alive from the troposphere on the parachute designed by Mullis. In the 60s, Mullis was carried away by experiments with hallucinogens, in particular LSD, which was not yet prohibited. Inventor He wrotethat “hallucinogens and psychedelics helped him make the most important discovery” to create PCR. As a graduate student, Mullis took up cosmological theories, in particular wrote A pseudo -scientific article that "time for observers from the Earth and for the observer outside the sphere emitting relict radiation should flow in different directions." Surprisingly, the article was accepted and printed in the journal Nature. By assumption Carey Mullis himself, the editorial office of the magazine should still be ashamed.

With a certain degree of assumption, we can say that the opening of the PCR was unintentional. Mullis Put The need to dismiss four out of seven laboratory employees in which he worked. He reflected on how to optimize and improve the process that would not be parted with valuable personnel. So he came to the conclusion that an expensive and long procedure for diagnosing the fetal pathologies should be simplified. The existing technology consisted in the fact that the selected DNA of the fetus was planted in the mouse egg, and the mouse that had already been born was analyzed for heavy pathologies. Mullis decided that you can do without a mouse. He invented a way to unwind DNA and a way to copy it necessary to obtain a sufficient volume of a substance number of times. Interestingly, the article sent to Nature about the invention of the PCR method was not adopted by the magazine. As a result, the article is not immediately, but there was Accepted and printed in Science, and already in 1993, Carey Mullis received The Nobel Prize in Chemistry for the opening of a polymerase chain reaction.

Hamster, Background, Pcr Tube, Tubes, Tube, Vial

It is interesting to note that along with the career of scientist, Kary Mullis considered the writer's career. Later on his site it is very colorful Described The moment when the idea of ​​the PCR came up with him: “California chestnuts stretched out their heavy flowers towards the highway 128. Pink and white shoots hanging from the spans of the headlights of my car seemed cold, but they were filled with warm broadcasts, prevailing in the area of ​​the West. It seemed that it was the night of chestnuts, but something else excited me. The tires of my little silver "honda" drove us through the mountains. My hands felt the road and turns. My thoughts returned to the laboratory. The DNA chains were folded and as if soared. Bright blue and pink images of electrical molecules arose somewhere between the mountain road and my eyes. ”

Despite the fact that the invention of the PCR test can be considered one of the most important discoveries of medicine, Carey Mullis had a very ambiguous reputation in scientific circles. In his book “Naked Dance in the Field of Reason” he Conducted Arguments against the ideas of global warming and exhaustion of the ozone layer, proved the scientificity of astrology, and also denied the connection between the human immunodeficiency virus and AIDS. In it, he wrote about the conspiracy of environmentalists, governments and scientists who promote their selfish interests. However, neither in booknor in numerous interviewnor on personal website Mullis did not say that the PCR should not be used to diagnose diseases. Moreover, such a thought contradicts the premise of the invention itself - Mullis was looking for a way to simplify and reduce the reduction of the diagnosis of diseases in the fetus. And, of course, he could not name testing on the Covid-19 scientific heresy and shame the scientists-Carey Mullis died August 7, 2019, while the first officially documented case of coronavirus infection happened Not earlier than November 2019.

Presumably, network conspiracyologists took the idea that the test, according to its creator, should not be used to diagnose diseases, from Articles John Lauritsen, in which he quotes the words of Carey Mullis: "The quantitative PCR is Oxymoron." Indeed, a polymerase chain reaction can only determine the presence of pathogen in the sample, but not its number. Lauritsen is questioned by one of the methods of antiretroviral therapy - the use of protease inhibitors - since at the time of writing the article, as he claims, they are not approved by the Office for Sanitary Supervision of the Quality of Food Products and Medicines of the United States (FDA). However, the author is mistaken - the first protease inhibitor received FDA patent December 6, 1995. Then he Writes: “What does the PCR do is choose a genetic sequence, and then extremely enhances it. She is like the search for a needle in a haystack. Like the antenna with an electronic amplifier, the PCR significantly enhances the signal, but also significantly enhances the noise. Since the strengthening is exponentially, the slightest error in measurement, the slightest pollution can lead to errors of many orders. ” That is, even Lauritsen does not mean that PCR cannot be used in the diagnosis of diseases, it only warns about the inadmissibility of the contamination (pollution) of the tool for taking the sample.

Thus, the Nobel laureate Carey Mullis never said that the PCR test invented by him is not suitable for the diagnosis of diseases, and even more so did not refute the possibility of mass PCR testing for a coronavirus infection, as he simply did not live up to the time when the SARS-COV-2 virus appeared in the human population. Moreover, he invented PCR precisely in order to accelerate and simplify the analysis for various diseases and malformations.

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